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POPSICLE- a software suite to determine population structure and to establish genotype-phenotype associations using Next-generation sequencing data | ![]() |
MAIN INDEX ANALYTICAL PIPELINE CONTACT SYSTEM REQUIREMENTS POPSICLE Package Download Manual pages in HTML format Used Case |
Generate necessary files to draw circos plots Prerequisites
It generates files required to draw circos plots How to run it? java -jar LPDtools.jar ConvertPopsicle2CircosHighlights -i polishedArrangedAncestryFile -o outputDirectory -j PopsicleBaselineFile -k clustersFile Here, -i is the ancestry file generated using the utility POPSICLEIntermediate , polished using the utility PolishPopsicle and arranged using the utility ArrangePopsicleByClustersFormed. -k is the clusters file generated using the utility PerformKmeansClustering and -j is the baseline file generated using the utility FindDivergenceFromBaseline utility of POPSICLE Output ![]() Outer concentric circle is local ancestries, middle concentric circle is global ancestries and inner concentric circle is clade assignment of the sample. Links demonstrate similarities between the clades |
CITATION: Jahangheer S. Shaik, Asis Khan and Michael E. Grigg, "POPSICLE: A Software Suite to Study Population Structure and Ancestral Determinants of Phenotypes using Whole genome Sequencing Data", submitted to PLoS special edition |